Localization of free fatty acids taken up by human platelets.

Human platelets take up and metabobound FFA. These findings suggested Iize long-chain free fatty acids (FFA). that a large portion of the platelet FFA Experiments in which platelets were uptake might be associated with the loaded with ‘4C-palmitate, homogenplatelet surface. Radioautography with ized, and then fractionated indicated electron microscopy using 3H-palmilarge amounts of membrane-bound tate-labeled platelets provided addiFFA. In other studies, platelet memtional evidence that much of the newly brane fractions took up FFA from incuincorporated FFA was associated with bation media containing albuminthe platelet surface.